rel Proto Oncogene Proteins
《英文msh詞典》rel Proto Oncogene Proteins
[入口詞] rel Proto Oncogene Proteins
[主題詞] Proto-Oncogene Proteins c-rel
[英文釋義] Cellular DNA-binding proteins encoded by the rel gene (GENES,REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B,I-kappa B,relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.